Pre-owned refurbished Instruments
At MS Vision we also sell and buy pre-owned lab equipment, in particular mass spectrometry systems from Waters, ThermoFisher and Sciex. The systems are checked and refurbished in-house, specified at manufacturers specifications and shipped and installed by specialized movers and our own experienced service specialist. Every system comes with installation and a 3 months warranty, longer warranties are available on request as well.
Buying a used mass spectrometry system has several advantages:
Apart from being more eco friendly, our pre-owned mass spectrometer offer you a much better return of investment due to lower purchasing costs than new systems. As these systems are also proven in their usage, you can easily find established methods, the software compatibility to your existing instruments is ensured and the shortcomings of a particular model are already known.
For buying systems, we are currently primarily interested in the following models of used mass spectrometers or complete LC-MS systems:
Waters:
- Synapt G1
- Synapt G2/G2-S/G2-Si
- Xevo TQ-S/TQ-XS
Sciex:
- 5500 QT/API
- 6500 QT/API
- 6500+ QT/API
ThermoFisher:
- QExactive classic/plus/HF
Contact us via the contact form or send us an email at info@msvision.com!
Currently available pre-owned systems:
All our instruments are sold including shipment, installation and three months warranty. Longer warranty is available on request. If you need items such as nitrogen generators, instrument benches or noise insulations please let us know and we can check whether we have something suitable for you.
Take on new analytical challenges and extend your research capability with the TripleTOF® 6600 Quadrupole Time-Of-Flight (QTOF) mass analyzer. The TripleTOF technology delivers high performance and reproducibility that can virtually detect any peptide. Ultra-fast acquisition rates allow you to collect high-resolution MS/MS data on every detectable analyte in your sample, giving you the potential you need to advance your research.
The TripleTOF 6600 System offers:
- A broad dynamic range of greater than 5 orders of magnitude
- Wide Q1 mass range with isolation for ions up to 2250 m/z
- Scan speed of up to 100 Hz (100 MS/MS spectra per second)
- MS/MS Resolution of equal or greater than 35,000 (FWHM)
- The TripleTOF 6600 System maximizes productivity with its real-time management of MS/MS acquisition time, based on the intensity of selected precursors.
- SWATH acquisition for label-free quantitation including variable window SWATH with up to 200 SWATH windows for optimal coverage of complex proteomics data
The instrument had a complete maintenance and a has a new orifice plate.
| Specifications | |
| Mass Range TOF | 5 – 40,000 m/z |
| Mass Selection Range Q1 | 5 – 2250 m/z |
| TOF-MS Mass Resolution and Acquisition Speed | ≥35,000 (FWHM) at 956 m/z, using 10 ms accumulation time |
| TOF-MS/MS Mass Resolution and Acquisition Speed | ≥30,000 (FWHM) at 813 m/z, and ≥25,000 (FWHM) at 195 m/z, using 10 ms accumulation time |
| Detector Type | 4-channel MCP detector with ADC signal processing for extended dynamic range |
| Flexible Data Acquisition Workflows | TOF-MS Information dependent acquisition (IDA) MS/MS Data Independent SWATH® Acquisition with fixed or variable Q1 isolation windows Targeted MRMHR workflow |
| Ionization Sources | IonDrive™ Turbo V, DuoSpray™ source, each with TurboIonSpray® or Atmospheric-pressure chemical ionization (APCI) probes available; NanoSpray® III source, Digital PicoView NanoSource |
| Variable Window SWATH® Acquisition | Data-Independent SWATH® Acquisition with variable window capabilities, allows for a large number of Q1 isolation windows at user controlled widths, up to 200 per cycle to achieve better specificity, even in complex samples. |
| Data File Portability | Condensed data file sizes simplify and streamline data storage and portability for sharing with colleagues, without losses in data quality, completeness or security |
The SYNAPT G2-S incorporates both high-sensitivity Waters StepWave™ ion transfer optics and Triwave® ion mobility technologies along with a suite of new informatics tools to take qualitative and quantitative high resolution performance to a new level.
SYNAPT G2-S provides a 30X improvement in signal intensity for mass spectral peaks, better than a 5X improvement in signal-to-noise, and up to a 10-fold improvement in limits of quantitation over previous-generation mass spectrometers. The significant increase in sensitivity, together with the unrivalled selectivity and analytical peak capacity made possible by ion mobility separations, allows the SYNAPT G2-S to identify and quantify sample analytes at lower concentrations than any other high resolution mass spectrometer and easily and routinely reveal details about complex samples that were previously difficult or impossible to obtain.
StepWave ion-transfer optics technology employs a revolutionary off-axis design for dramatically increasing the efficiency of ion transfer from the ion source to the MS analyzer, while at the same time actively eliminating undesirable neutral contaminants. The resulting sensitivity improvement is critical, for example, in metabolite identification where the goal is to find, identify and quantify all metabolites in a sample.
The instrument is equipped with a 4k quadrupole and currently installed and running in our lab in Almere.
| Specifications | |
| TOF Mass Resolution | >20.000 FWHM @ m/z 956 in resolution mode, >40.000 FWHM in high resolution mode |
| Mass range | 20 – 100.000 m/z in resolution mode, 20 – 32.000 m/z in high resolution mode |
| Quadrupole mass range | 20 – 4.000 m/z |
| Quadrupole transmission in non-resolving mode | 20 – 16.000 m/z for 4k quadrupole |
| Mass accuracy | better than 1 ppm RMS with internal lockmass calibration |
| Acquisition rate | Up to 30 Hz |
| Dynamic range | at least 4 orders of magnitude |
| Measurement modes | DDA, DIA (MS(E), IMS-TOF |
| MS to MS/MS switching time | 5 ms |
| IMS functions | Separation of ions based on their mobility Time Aligned Parallel (TAP) fragmentation Drift time measurements |
The Waters Xevo TQ Mass Spectrometer is an advanced, bench-top, tandem quadrupole mass spectrometer designed for ultra high performance LC-MS applications. Unlike conventional tandem quadrupole mass spectrometers, the Xevo TQ MS utilizes unique T-Wave and ScanWave enabled collsion cell technology to provide a highly flexible analytical tool capable of supporting both quantitative and qualitative studies on a single MS platform. The Xevo TQ MS is a robust platform for quantitative LC-MS/MS, featuring high speed MRM, with enhanced full scan spectral acquisition modes providing additional qualitative LC-MS/MS capabilities.
| Specifications | |
| TOF Mass Resolution | >20.000 FWHM @ m/z 956 in resolution mode, >40.000 FWHM in high resolution mode |
| Mass range | 2 – 2.048 m/z |
| Scan speed | Up to 10.000 Da/s |
| Mass stability | less than 0,1 amu over 24h |
| Linearity of response | >five orders of magnitude from the limit of detection |
| Polarity switching time | 20 ms |
| MS to MS/MS switching | 5 ms |
| MRM acquisition rate | Minimum dwell time of 1 ms per MRM channel |
| Number of MRM channels | Up to 16.384 MRM channels |
| Aquisition | Full scan MS Product ion scan (ScanWave enhanced) Precursor ion scan Constant neutral loss scan Selected ion monitoring (SIM) Multiple reaction monitoring (MRM) |
| Mass resolution | Automatically adjusted to desired resolution (0.40 Da, 0.75 Da or 1.00 Da FWHM) |
| MRM sensitivity (ESI+) | 50 fg reserpine on-column S/N>500:1 |
Acquity series has set a new standard in liquid chromatography, introducing the UPLC technology, which has been adopted successfully in laboratories around the world for the most demanding separations. Acquity UPLC systems are extremely robust, dependable, and reproducible.
- Work at higher efficiencies with a much wider range of linear velocities, flow rates, and backpressures
- Higher flow rates and increased throughput result in superior resolution and sensitivity
- Eliminate significant time and cost per sample, while improving quality of results
In the case an LC system is purchased, in combination with an MS system, a 10 % discount will be applied on the purchase price of the HPLC.
MS Vision has this complete Acquity UPLC stack on offer, comprising the following hardware & software components:
- Binary Solvent Manager
- Column Manager
- Sample Manager, or Sample Organiser
- option: PDA detector
The system can be upgrade to a 2-Dimensional UPLC system, via the addition of the following extra units: Binary Solvent Manager and Column Manager. Should a 2D UPLC system be of interest, please request information.
The system will be delivered complete and ready to directly accept installation. The Acquity forms an ideal platform in combination with the following mass specs, also on offer: Synapt series, XEVO Q-ToF series and the Q-ToF Premier.
If purchased, in combination with an MS system, a 10 % discount is applicable on the purchase price of the LC system.
The Shimadzu Nexera family is a modular all-round LC system, that can be combined flexibly with all types of mass analyzers. Micro-volume plungers provide precise solvent delivery and low injection volumes to achieve excellent injection reproducibility and extremely low carryover. The outstanding core performance capabilities of the Nexera provide highly reliable data in all types of application fields.
MS Vision has this complete Shimadzu Nexera HPLC stack on offer, comprising the following hardware & software components:
- up to 4 x LC20 ADXR LC pumps (request number of pumps on request)
- LC CTO-20A column oven
- LC DGU 20A3 3-channel vacuum degassing unit, or
- LC DGU 20A5 5-channel vacuum degassing unit
- LC CBM 20A PC interface / system controller
- SIL 30A CMP auto sampler
- SPD 20A UV-VIS detector
The Nexera forms an ideal platform in combination with the following mass spectrometers: AB Sciex blueline QqQ and QTrap, AB Sciex 5600/6600 Tripletof, Waters TQ-S or Synapt, Thermo TSQ Quantiva or Quantum Ultra.